Bubbles on the skin following renal transplant.

Volume 84, Number 9 www.aafp.org/afp American Family Physician 1035 A 51-year-old man developed a mild fever and several serous vesicles on an erythematous base on his trunk (Figures 1 and 2) three months after having a renal transplant. During the following 10 days, similar lesions developed on his neck, upper arms, lower back, and inner thigh. The patient had the transplant because of end-stage renal disease related to interstitial nephritis. He had received a kidney from his father and was on immunosuppressive therapy. Physical examination was otherwise normal, with no evidence of secondary infection. Complete blood count, liver enzyme level, and serum creatinine level were normal. A Tzanck test from a vesicle showed giant cells and acantholytic cells.